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Resolving dual binding conformations of cellulosome cohesin-dockerin complexes using single-molecule force spectroscopy

Receptor-ligand pairs are ordinarily thought to interact through a lock and key mechanism, where a unique molecular conformation is formed upon binding. Contrary to this paradigm, cellulosomal cohesin-dockerin (Coh-Doc) pairs are believed to interact through redundant dual binding modes consisting o...

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Detalles Bibliográficos
Autores principales:	Jobst, Markus A, Milles, Lukas F, Schoeler, Constantin, Ott, Wolfgang, Fried, Daniel B, Bayer, Edward A, Gaub, Hermann E, Nash, Michael A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728124/ https://www.ncbi.nlm.nih.gov/pubmed/26519733 http://dx.doi.org/10.7554/eLife.10319

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