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Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling
In the striatum, signaling via G protein-coupled neurotransmitter receptors is essential for motor control. Critical to this process is the effector enzyme adenylyl cyclase type 5 (AC5) that produces second messenger cAMP upon receptor-mediated activation by G protein Golf. However, the molecular or...
Autores principales: | Xie, Keqiang, Masuho, Ikuo, Shih, Chien-Cheng, Cao, Yan, Sasaki, Keita, Lai, Chun Wan J, Han, Pyung-Lim, Ueda, Hiroshi, Dessauer, Carmen W, Ehrlich, Michelle E, Xu, Baoji, Willardson, Barry M, Martemyanov, Kirill A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728126/ https://www.ncbi.nlm.nih.gov/pubmed/26613416 http://dx.doi.org/10.7554/eLife.10451 |
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