Phosphopeptide interactions with BRCA1 BRCT domains: More than just a motif

BRCA1 BRCT domains function as phosphoprotein-binding modules for recognition of the phosphorylated protein-sequence motif pSXXF. While the motif interaction interface provides strong anchor points for binding, protein regions outside the motif have recently been found to be important for binding af...

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Detalles Bibliográficos
Autores principales: Wu, Qian, Jubb, Harry, Blundell, Tom L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728184/
https://www.ncbi.nlm.nih.gov/pubmed/25701377
http://dx.doi.org/10.1016/j.pbiomolbio.2015.02.003

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