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Alternative modulation of protein–protein interactions by small molecules
Protein–protein interactions (PPI) have become increasingly popular drug targets, with a number of promising compounds currently in clinical trials. Recent research shows, that PPIs can be modulated in more ways than direct inhibition, where novel non-competitive modes of action promise a solution f...
Autores principales: | Fischer, Gerhard, Rossmann, Maxim, Hyvönen, Marko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728186/ https://www.ncbi.nlm.nih.gov/pubmed/25935873 http://dx.doi.org/10.1016/j.copbio.2015.04.006 |
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