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Drugging PI3K in cancer: refining targets and therapeutic strategies

The phosphatidylinositol-3 kinase (PI3K) pathway is one of the most frequently activated pathogenic signalling routes in human cancers, making it a rational and important target for innovative anticancer drug development and precision medicine. The three main classes of PI3K inhibitors currently in...

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Detalles Bibliográficos
Autores principales:	Yap, Timothy A, Bjerke, Lynn, Clarke, Paul A, Workman, Paul
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Science Ltd 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728196/ https://www.ncbi.nlm.nih.gov/pubmed/26117819 http://dx.doi.org/10.1016/j.coph.2015.05.016

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