Cdc42 and k-Ras Control Endothelial Tubulogenesis through Apical Membrane and Cytoskeletal Polarization: Novel Stimulatory Roles for GTPase Effectors, the Small GTPases, Rac2 and Rap1b, and Inhibitory Influence of Arhgap31 and Rasa1

A critical and understudied property of endothelial cells is their ability to form lumens and tube networks. Although considerable information has been obtained concerning these issues, including the role of Cdc42 and Rac1 and their effectors such as Pak2, Pak4, Par6b, and co-regulators such as inte...

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Detalles Bibliográficos
Autores principales: Norden, Pieter R., Kim, Dae Joong, Barry, David M., Cleaver, Ondine B., Davis, George E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728208/
https://www.ncbi.nlm.nih.gov/pubmed/26812085
http://dx.doi.org/10.1371/journal.pone.0147758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728208/
https://www.ncbi.nlm.nih.gov/pubmed/26812085
http://dx.doi.org/10.1371/journal.pone.0147758

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