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A Tutorial on RxODE: Simulating Differential Equation Pharmacometric Models in R
This tutorial presents the application of an R package, RxODE, that facilitates quick, efficient simulations of ordinary differential equation models completely within R. Its application is illustrated through simulation of design decision effects on an adaptive dosing regimen. The package provides...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728294/ https://www.ncbi.nlm.nih.gov/pubmed/26844010 http://dx.doi.org/10.1002/psp4.12052 |