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Prevalence of HCV NS3 pre-treatment resistance associated amino acid variants within a Scottish cohort
BACKGROUND: Protease inhibitors (PI) including boceprevir, telaprevir and simeprevir have revolutionised HCV genotype 1 treatment since their introduction. A number of pre-treatment resistance associated amino acid variants (RAVs) and polymorphisms have been associated with reduced response to treat...
Autores principales: | Shepherd, Samantha J., Abdelrahman, Tamer, MacLean, Alasdair R., Thomson, Emma C., Aitken, Celia, Gunson, Rory N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728298/ https://www.ncbi.nlm.nih.gov/pubmed/25766988 http://dx.doi.org/10.1016/j.jcv.2015.02.005 |
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