Pentamidine rescues contractility and rhythmicity in a Drosophila model of myotonic dystrophy heart dysfunction

Up to 80% of individuals with myotonic dystrophy type 1 (DM1) will develop cardiac abnormalities at some point during the progression of their disease, the most common of which is heart blockage of varying degrees. Such blockage is characterized by conduction defects and supraventricular and ventric...

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Detalles Bibliográficos
Autores principales: Chakraborty, Mouli, Selma-Soriano, Estela, Magny, Emile, Couso, Juan Pablo, Pérez-Alonso, Manuel, Charlet-Berguerand, Nicolas, Artero, Ruben, Llamusi, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728315/
https://www.ncbi.nlm.nih.gov/pubmed/26515653
http://dx.doi.org/10.1242/dmm.021428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728315/
https://www.ncbi.nlm.nih.gov/pubmed/26515653
http://dx.doi.org/10.1242/dmm.021428

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