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A novel mouse model of tuberous sclerosis complex (TSC): eye-specific Tsc1-ablation disrupts visual-pathway development

Tuberous sclerosis complex (TSC) is an autosomal dominant syndrome that is best characterised by neurodevelopmental deficits and the presence of benign tumours (called hamartomas) in affected organs. This multi-organ disorder results from inactivating point mutations in either the TSC1 or the TSC2 g...

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Detalles Bibliográficos
Autores principales:	Jones, Iwan, Hägglund, Anna-Carin, Törnqvist, Gunilla, Nord, Christoffer, Ahlgren, Ulf, Carlsson, Leif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728318/ https://www.ncbi.nlm.nih.gov/pubmed/26449264 http://dx.doi.org/10.1242/dmm.021972

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