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Hox11 genes regulate postnatal longitudinal bone growth and growth plate proliferation

Hox genes are critical regulators of skeletal development and Hox9-13 paralogs, specifically, are necessary for appendicular development along the proximal to distal axis. Loss of function of both Hoxa11 and Hoxd11 results in severe malformation of the forelimb zeugopod. In the radius and ulna of th...

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Detalles Bibliográficos
Autores principales:	Pineault, Kyriel M., Swinehart, Ilea T., Garthus, Kayla N., Ho, Edward, Yao, Qing, Schipani, Ernestina, Kozloff, Kenneth M., Wellik, Deneen M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728342/ https://www.ncbi.nlm.nih.gov/pubmed/26500224 http://dx.doi.org/10.1242/bio.012500

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