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Generation of primitive neural stem cells from human fibroblasts using a defined set of factors

In mice, leukemia inhibitory factor (LIF)-dependent primitive neural stem cells (NSCs) have a higher neurogenic potential than bFGF-dependent definitive NSCs. Therefore, expandable primitive NSCs are required for research and for the development of therapeutic strategies for neurological diseases. T...

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Detalles Bibliográficos
Autores principales:	Miura, Takumi, Sugawara, Tohru, Fukuda, Atsushi, Tamoto, Ryo, Kawasaki, Tomoyuki, Umezawa, Akihiro, Akutsu, Hidenori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists 2015
Materias:	Methods & Techniques
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728346/ https://www.ncbi.nlm.nih.gov/pubmed/26490674 http://dx.doi.org/10.1242/bio.013151

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