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Mindbomb 2 is dispensable for embryonic development and Notch signalling in zebrafish

The Mindbomb E3 ubiquitin protein ligase (Mib) family of proteins, Mib1 and Mib2, are RING finger ubiquitin ligases that share specific substrates. Mib1 is known to play essential roles in Notch signalling by ubiquitinating Notch ligands in vivo. Conversely, the functions of Mib2 in vivo are not ful...

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Detalles Bibliográficos
Autores principales: Mikami, Shohei, Nakaura, Mizuki, Kawahara, Atsuo, Mizoguchi, Takamasa, Itoh, Motoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728363/
https://www.ncbi.nlm.nih.gov/pubmed/26519518
http://dx.doi.org/10.1242/bio.014225

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