Cargando…

Activating mutations in CTNNB1 in aldosterone producing adenomas

Primary aldosteronism (PA) is the most common cause of secondary hypertension with a prevalence of 5–10% in unreferred hypertensive patients. Aldosterone producing adenomas (APAs) constitute a large proportion of PA cases and represent a surgically correctable form of the disease. The WNT signaling...

Descripción completa

Detalles Bibliográficos
Autores principales: Åkerström, Tobias, Maharjan, Rajani, Sven Willenberg, Holger, Cupisti, Kenko, Ip, Julian, Moser, Ana, Stålberg, Peter, Robinson, Bruce, Alexander Iwen, K., Dralle, Henning, Walz, Martin K., Lehnert, Hendrik, Sidhu, Stan, Gomez-Sanchez, Celso, Hellman, Per, Björklund, Peyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728393/
https://www.ncbi.nlm.nih.gov/pubmed/26815163
http://dx.doi.org/10.1038/srep19546