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A novel method for evaluating antibody-dependent cell-mediated cytotoxicity by flowcytometry using cryopreserved human peripheral blood mononuclear cells

Analyzing the cytotoxic functions of effector cells, such as NK cells against target cancer cells, is thought to be necessary for predicting the clinical efficacy of antibody-dependent cellular cytotoxicity (ADCC) -dependent antibody therapy. The (51)Cr release assay has long been the most widely us...

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Detalles Bibliográficos
Autores principales:	Yamashita, Makiko, Kitano, Shigehisa, Aikawa, Hiroaki, Kuchiba, Aya, Hayashi, Mitsuhiro, Yamamoto, Noboru, Tamura, Kenji, Hamada, Akinobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728441/ https://www.ncbi.nlm.nih.gov/pubmed/26813960 http://dx.doi.org/10.1038/srep19772

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