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Cell Proliferation in Neuroblastoma
Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728460/ https://www.ncbi.nlm.nih.gov/pubmed/26771642 http://dx.doi.org/10.3390/cancers8010013 |
| _version_ | 1782412114756894720 |
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| author | Stafman, Laura L. Beierle, Elizabeth A. |
| author_facet | Stafman, Laura L. Beierle, Elizabeth A. |
| author_sort | Stafman, Laura L. |
| collection | PubMed |
| description | Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle. Novel therapeutic strategies directed toward these targets in neuroblastoma are discussed. |
| format | Online Article Text |
| id | pubmed-4728460 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | MDPI |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-47284602016-02-08 Cell Proliferation in Neuroblastoma Stafman, Laura L. Beierle, Elizabeth A. Cancers (Basel) Review Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle. Novel therapeutic strategies directed toward these targets in neuroblastoma are discussed. MDPI 2016-01-12 /pmc/articles/PMC4728460/ /pubmed/26771642 http://dx.doi.org/10.3390/cancers8010013 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
| spellingShingle | Review Stafman, Laura L. Beierle, Elizabeth A. Cell Proliferation in Neuroblastoma |
| title | Cell Proliferation in Neuroblastoma |
| title_full | Cell Proliferation in Neuroblastoma |
| title_fullStr | Cell Proliferation in Neuroblastoma |
| title_full_unstemmed | Cell Proliferation in Neuroblastoma |
| title_short | Cell Proliferation in Neuroblastoma |
| title_sort | cell proliferation in neuroblastoma |
| topic | Review |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728460/ https://www.ncbi.nlm.nih.gov/pubmed/26771642 http://dx.doi.org/10.3390/cancers8010013 |
| work_keys_str_mv | AT stafmanlaural cellproliferationinneuroblastoma AT beierleelizabetha cellproliferationinneuroblastoma |