Atrasentan increased the expression of klotho by mediating miR-199b-5p and prevented renal tubular injury in diabetic nephropathy

Atrasentan is a promising therapy for treating diabetic nephropathy (DN). Here we evaluated whether atrasentan down-regulated the miR-199b-5p expression, thereby increasing klotho and preventing renal tubular injury in DN. One-hundred patients with type 2 diabetes mellitus (T2DM) and 40 healthy subj...

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Detalles Bibliográficos
Autores principales: Kang, Wen-Ling, Xu, Gao-Si
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728478/
https://www.ncbi.nlm.nih.gov/pubmed/26813039
http://dx.doi.org/10.1038/srep19979

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728478/
https://www.ncbi.nlm.nih.gov/pubmed/26813039
http://dx.doi.org/10.1038/srep19979

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