The dual function of PRMT1 in modulating epithelial-mesenchymal transition and cellular senescence in breast cancer cells through regulation of ZEB1

Although the involvement of protein arginine methyltransferase 1 (PRMT1) in tumorigenesis has been reported, its roles in breast cancer progression and metastasis has not been elucidated. Here we identified PRMT1 as a key regulator of the epithelial-mesenchymal transition (EMT) in breast cancer. We...

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Detalles Bibliográficos
Autores principales: Gao, Yanyan, Zhao, Yaping, Zhang, Juechao, Lu, Yang, Liu, Xin, Geng, Pengyu, Huang, Baiqu, Zhang, Yu, Lu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728496/
https://www.ncbi.nlm.nih.gov/pubmed/26813495
http://dx.doi.org/10.1038/srep19874

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