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Reactive Oxygen Species as Additional Determinants for Cytotoxicity of Clostridium difficile Toxins A and B

Clostridium difficile infections can induce mild to severe diarrhoea and the often associated characteristic pseudomembranous colitis. Two protein toxins, the large glucosyltransferases TcdA and TcdB, are the main pathogenicity factors that can induce all clinical symptoms in animal models. The clas...

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Detalles Bibliográficos
Autores principales:	Frädrich, Claudia, Beer, Lara-Antonia, Gerhard, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728547/ https://www.ncbi.nlm.nih.gov/pubmed/26797634 http://dx.doi.org/10.3390/toxins8010025

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