The CaSm (LSm1) oncogene promotes transformation, chemoresistance and metastasis of pancreatic cancer cells

The cancer-associated Sm-like (CaSm) oncogene is overexpressed in 87% of human pancreatic tumor samples and CaSm knockdown has demonstrated therapeutic efficacy in murine models of pancreatic cancer. Evidence indicates that CaSm modulates messenger RNA degradation; however, its target genes and the...

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Detalles Bibliográficos
Autores principales: Little, E C, Camp, E R, Wang, C, Watson, P M, Watson, D K, Cole, D J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728675/
https://www.ncbi.nlm.nih.gov/pubmed/26751936
http://dx.doi.org/10.1038/oncsis.2015.45

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728675/
https://www.ncbi.nlm.nih.gov/pubmed/26751936
http://dx.doi.org/10.1038/oncsis.2015.45

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