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Integrin-mediated resistance to epidermal growth factor receptor-targeted therapy: an inflammatory situation
Targeting the function of epidermal growth factor receptor (EGFR) has failed as an effective clinical option for breast cancer. Understanding the drivers of inherent resistance has been a challenge. One possible mechanism is the acquisition of stem-like properties through the process of epithelial-m...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728772/ https://www.ncbi.nlm.nih.gov/pubmed/25255930 http://dx.doi.org/10.1186/s13058-014-0448-0 |