GEP analysis validates high risk MDS and acute myeloid leukemia post MDS mice models and highlights novel dysregulated pathways

BACKGROUND: In spite of the recent discovery of genetic mutations in most myelodysplasic (MDS) patients, the pathophysiology of these disorders still remains poorly understood, and only few in vivo models are available to help unravel the disease. METHODS: We performed global specific gene expressio...

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Detalles Bibliográficos
Autores principales: Guerenne, Laura, Beurlet, Stéphanie, Said, Mohamed, Gorombei, Petra, Le Pogam, Carole, Guidez, Fabien, de la Grange, Pierre, Omidvar, Nader, Vanneaux, Valérie, Mills, Ken, Mufti, Ghulam J, Sarda-Mantel, Laure, Noguera, Maria Elena, Pla, Marika, Fenaux, Pierre, Padua, Rose Ann, Chomienne, Christine, Krief, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728810/
https://www.ncbi.nlm.nih.gov/pubmed/26817437
http://dx.doi.org/10.1186/s13045-016-0235-8

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