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Correlation of plasma crizotinib trough concentration with adverse events in patients with anaplastic lymphoma kinase positive non-small-cell lung cancer
BACKGROUND: Crizotinib, an ATP-competitive receptor tyrosine kinase inhibitor of both anaplastic lymphoma kinase (ALK) and the hepatocyte growth factor receptor, commonly causes several adverse events (AEs). The clinical utility of measuring the plasma concentration of crizotinib in patients with no...
Autores principales: | Kurata, Yasuko, Miyauchi, Narumi, Suno, Manabu, Ito, Takahiro, Sendo, Toshiaki, Kiura, Katsuyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728826/ https://www.ncbi.nlm.nih.gov/pubmed/26819719 http://dx.doi.org/10.1186/s40780-014-0008-x |
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