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The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma

The main purpose of this study is to know the effect of three different photon energies viz., 6, 10, and 15 mega voltage (MV) on RapidArc (RA) planning for deep-seated cervix tumor and to develop clinically acceptable RA plans with suitable photon energy. RA plans were generated for 6, 10, and 15 MV...

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Autores principales: Kumar, Lalit, Yadav, Girigesh, Raman, Kothanda, Bhushan, Manindra, Pal, Manoj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728891/
https://www.ncbi.nlm.nih.gov/pubmed/26865756
http://dx.doi.org/10.4103/0971-6203.170787
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author Kumar, Lalit
Yadav, Girigesh
Raman, Kothanda
Bhushan, Manindra
Pal, Manoj
author_facet Kumar, Lalit
Yadav, Girigesh
Raman, Kothanda
Bhushan, Manindra
Pal, Manoj
author_sort Kumar, Lalit
collection PubMed
description The main purpose of this study is to know the effect of three different photon energies viz., 6, 10, and 15 mega voltage (MV) on RapidArc (RA) planning for deep-seated cervix tumor and to develop clinically acceptable RA plans with suitable photon energy. RA plans were generated for 6, 10, and 15 MV photon energies for twenty patients reported with cervix carcinoma. RA plans were evaluated in terms of planning target volume (PTV) coverage, dose to organs at risk (OARs), conformity index (CI), homogeneity index (HI), gradient measure, external volume index of dose distribution produced, total number of monitor units (MUs), nontumor integral dose (ID), and low dose volume of normal tissue. A two-sample paired t-test was performed to compare the dosimetric parameters of RA plans. Irrespective of photon energy used for RA planning, plans were dosimetrically similar in terms of PTV coverage, OARs sparing, CI and HI. The numbers of MUs were 13.4 ± 1.4% and 18.2 ± 1.5% higher and IDs were 2.7 ± 0.8% and 3.7 ± 0.9% higher in 6 MV plans in comparison to that in the 10 and 15 MV plans, respectively. V(1Gy), V(2Gy), V(3Gy), and V(4Gy) were higher in 6 MV plans in comparison to that in 10 and 15 MV plans. Based on this study, 6 MV photon beam is a good choice for RA planning in case of cervix carcinoma, as it does not deliver additional exposure to patients caused by photoneutrons produced in high energy beams.
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spelling pubmed-47288912016-02-10 The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma Kumar, Lalit Yadav, Girigesh Raman, Kothanda Bhushan, Manindra Pal, Manoj J Med Phys Original Article The main purpose of this study is to know the effect of three different photon energies viz., 6, 10, and 15 mega voltage (MV) on RapidArc (RA) planning for deep-seated cervix tumor and to develop clinically acceptable RA plans with suitable photon energy. RA plans were generated for 6, 10, and 15 MV photon energies for twenty patients reported with cervix carcinoma. RA plans were evaluated in terms of planning target volume (PTV) coverage, dose to organs at risk (OARs), conformity index (CI), homogeneity index (HI), gradient measure, external volume index of dose distribution produced, total number of monitor units (MUs), nontumor integral dose (ID), and low dose volume of normal tissue. A two-sample paired t-test was performed to compare the dosimetric parameters of RA plans. Irrespective of photon energy used for RA planning, plans were dosimetrically similar in terms of PTV coverage, OARs sparing, CI and HI. The numbers of MUs were 13.4 ± 1.4% and 18.2 ± 1.5% higher and IDs were 2.7 ± 0.8% and 3.7 ± 0.9% higher in 6 MV plans in comparison to that in the 10 and 15 MV plans, respectively. V(1Gy), V(2Gy), V(3Gy), and V(4Gy) were higher in 6 MV plans in comparison to that in 10 and 15 MV plans. Based on this study, 6 MV photon beam is a good choice for RA planning in case of cervix carcinoma, as it does not deliver additional exposure to patients caused by photoneutrons produced in high energy beams. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4728891/ /pubmed/26865756 http://dx.doi.org/10.4103/0971-6203.170787 Text en Copyright: © Journal of Medical Physics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kumar, Lalit
Yadav, Girigesh
Raman, Kothanda
Bhushan, Manindra
Pal, Manoj
The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title_full The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title_fullStr The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title_full_unstemmed The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title_short The dosimetric impact of different photon beam energy on RapidArc radiotherapy planning for cervix carcinoma
title_sort dosimetric impact of different photon beam energy on rapidarc radiotherapy planning for cervix carcinoma
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728891/
https://www.ncbi.nlm.nih.gov/pubmed/26865756
http://dx.doi.org/10.4103/0971-6203.170787
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