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A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography

The detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dua...

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Autores principales: Khoshakhlagh, Mohammad, Islamian, Jalil Pirayesh, Abedi, Mohammad, Mahmoudian, Babak, Mardanshahi, Ali Reza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729008/
https://www.ncbi.nlm.nih.gov/pubmed/26912973
http://dx.doi.org/10.4103/1450-1147.167588
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author Khoshakhlagh, Mohammad
Islamian, Jalil Pirayesh
Abedi, Mohammad
Mahmoudian, Babak
Mardanshahi, Ali Reza
author_facet Khoshakhlagh, Mohammad
Islamian, Jalil Pirayesh
Abedi, Mohammad
Mahmoudian, Babak
Mardanshahi, Ali Reza
author_sort Khoshakhlagh, Mohammad
collection PubMed
description The detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dual head variable angle SPECT imaging system with a low energy high resolution (LEHR) collimator. The Planar and SPECT scans for a (99m)Tc point source and a Jaszczak Phantom with the both experiment and simulated systems were prepared and after verification and validation of the simulated system, the similar scans of the phantoms were compared (from the point of view of the images’ quality), namely, the simulated system with the detectors including bismuth germanate (BGO), yttrium aluminum garnet (YAG:Ce), Cerium-doped yttrium aluminum garnet (YAG:Ce), yttrium aluminum perovslite (YAP:Ce), lutetium aluminum garnet (LuAG:Ce), cerium activated lanthanum bromide (LaBr3), cadmium zinc telluride (CZT), and sodium iodide activated with thallium [NaI(Tl)]. The parameters of full width at half maximum (FWHM), energy and special resolution, sensitivity, and also the comparison of images’ quality by the structural similarity (SSIM) algorithm with the Zhou Wang and Rouse/Hemami methods were analyzed. FWHMs for the crystals were calculated at 13.895, 14.321, 14.310, 14.322, 14.184, and 14.312 keV and the related energy resolutions obtained 9.854, 10.229, 10.221, 10.230, 10.131, and 10.223 %, respectively. Finally, SSIM indexes for comparison of the phantom images were calculated at 0.22172, 0.16326, 0.18135, 0.17301, 0.18412, and 0.20433 as compared to NaI(Tl). The results showed that BGO and LuAG: Ce crystals have high sensitivity and resolution, and better image quality as compared to other scintillation crystals.
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spelling pubmed-47290082016-02-24 A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography Khoshakhlagh, Mohammad Islamian, Jalil Pirayesh Abedi, Mohammad Mahmoudian, Babak Mardanshahi, Ali Reza World J Nucl Med Original Article The detector is a critical component of the single photon emission computed tomography (SPECT) imaging system for giving accurate information from the exact pattern of radionuclide distribution in the target organ. The SIMIND Monte Carlo program was utilized for the simulation of a Siemen's dual head variable angle SPECT imaging system with a low energy high resolution (LEHR) collimator. The Planar and SPECT scans for a (99m)Tc point source and a Jaszczak Phantom with the both experiment and simulated systems were prepared and after verification and validation of the simulated system, the similar scans of the phantoms were compared (from the point of view of the images’ quality), namely, the simulated system with the detectors including bismuth germanate (BGO), yttrium aluminum garnet (YAG:Ce), Cerium-doped yttrium aluminum garnet (YAG:Ce), yttrium aluminum perovslite (YAP:Ce), lutetium aluminum garnet (LuAG:Ce), cerium activated lanthanum bromide (LaBr3), cadmium zinc telluride (CZT), and sodium iodide activated with thallium [NaI(Tl)]. The parameters of full width at half maximum (FWHM), energy and special resolution, sensitivity, and also the comparison of images’ quality by the structural similarity (SSIM) algorithm with the Zhou Wang and Rouse/Hemami methods were analyzed. FWHMs for the crystals were calculated at 13.895, 14.321, 14.310, 14.322, 14.184, and 14.312 keV and the related energy resolutions obtained 9.854, 10.229, 10.221, 10.230, 10.131, and 10.223 %, respectively. Finally, SSIM indexes for comparison of the phantom images were calculated at 0.22172, 0.16326, 0.18135, 0.17301, 0.18412, and 0.20433 as compared to NaI(Tl). The results showed that BGO and LuAG: Ce crystals have high sensitivity and resolution, and better image quality as compared to other scintillation crystals. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4729008/ /pubmed/26912973 http://dx.doi.org/10.4103/1450-1147.167588 Text en Copyright: © World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Khoshakhlagh, Mohammad
Islamian, Jalil Pirayesh
Abedi, Mohammad
Mahmoudian, Babak
Mardanshahi, Ali Reza
A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title_full A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title_fullStr A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title_full_unstemmed A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title_short A Study on Determination of an Optimized Detector for Single Photon Emission Computed Tomography
title_sort study on determination of an optimized detector for single photon emission computed tomography
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729008/
https://www.ncbi.nlm.nih.gov/pubmed/26912973
http://dx.doi.org/10.4103/1450-1147.167588
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