Comparison of [(15)O] H(2)O Positron Emission Tomography and Functional Magnetic Resonance Imaging in Activation Studies

[(15)O] H(2)O positron emission tomography (PET) has long been out of use in activation studies on the brain. Indeed, it is true that blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has better spatial resolution and temporal resolution than PET, as well as no radiati...

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Detalles Bibliográficos
Autores principales: Kameyama, Masashi, Murakami, Koji, Jinzaki, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729011/
https://www.ncbi.nlm.nih.gov/pubmed/26912971
http://dx.doi.org/10.4103/1450-1147.172139
Descripción
Sumario:[(15)O] H(2)O positron emission tomography (PET) has long been out of use in activation studies on the brain. Indeed, it is true that blood oxygen level dependent (BOLD) functional magnetic resonance imaging (fMRI) has better spatial resolution and temporal resolution than PET, as well as no radiation exposure. However, PET and fMRI differ in their scope. Compared to fMRI, [(15)O] H(2)O PET offers advantages such as being quantifiable, less deteriorated by movement, and allowing for longitudinal studies. This article aimed to reassess the merits of PET in this context.

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