Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis

The retrospective study aimed to evaluate the diagnostic value of bronchial brushing and sputum using acid fast bacilli smear, mycobacterial culture and real-time PCR in detection of pediatric pulmonary tuberculosis, sensitivity and specificity of bronchial brushing and sputum examined by the three...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Qiao-pei, Ren, Shi-feng, Wang, Xin-feng, Wang, Mao-shui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729046/
https://www.ncbi.nlm.nih.gov/pubmed/26817961
http://dx.doi.org/10.1186/s13052-016-0221-3
_version_ 1782412216374394880
author Chen, Qiao-pei
Ren, Shi-feng
Wang, Xin-feng
Wang, Mao-shui
author_facet Chen, Qiao-pei
Ren, Shi-feng
Wang, Xin-feng
Wang, Mao-shui
author_sort Chen, Qiao-pei
collection PubMed
description The retrospective study aimed to evaluate the diagnostic value of bronchial brushing and sputum using acid fast bacilli smear, mycobacterial culture and real-time PCR in detection of pediatric pulmonary tuberculosis, sensitivity and specificity of bronchial brushing and sputum examined by the three methods were calculated and compared to each other. Data showed there were no significant difference in sensitivity between bronchial brushing and matched sputum using each method. But the specificity of real-time PCR on bronchial brushing was lower than on sputum. Compared with bronchial brushing, sputum was better specimen in detection of pediatric pulmonary tuberculosis.
format Online
Article
Text
id pubmed-4729046
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-47290462016-01-28 Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis Chen, Qiao-pei Ren, Shi-feng Wang, Xin-feng Wang, Mao-shui Ital J Pediatr Letter to the Editor The retrospective study aimed to evaluate the diagnostic value of bronchial brushing and sputum using acid fast bacilli smear, mycobacterial culture and real-time PCR in detection of pediatric pulmonary tuberculosis, sensitivity and specificity of bronchial brushing and sputum examined by the three methods were calculated and compared to each other. Data showed there were no significant difference in sensitivity between bronchial brushing and matched sputum using each method. But the specificity of real-time PCR on bronchial brushing was lower than on sputum. Compared with bronchial brushing, sputum was better specimen in detection of pediatric pulmonary tuberculosis. BioMed Central 2016-01-27 /pmc/articles/PMC4729046/ /pubmed/26817961 http://dx.doi.org/10.1186/s13052-016-0221-3 Text en © Chen et al. 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Letter to the Editor
Chen, Qiao-pei
Ren, Shi-feng
Wang, Xin-feng
Wang, Mao-shui
Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title_full Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title_fullStr Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title_full_unstemmed Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title_short Comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
title_sort comparison of bronchial brushing and sputum in detection of pediatric pulmonary tuberculosis
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729046/
https://www.ncbi.nlm.nih.gov/pubmed/26817961
http://dx.doi.org/10.1186/s13052-016-0221-3
work_keys_str_mv AT chenqiaopei comparisonofbronchialbrushingandsputumindetectionofpediatricpulmonarytuberculosis
AT renshifeng comparisonofbronchialbrushingandsputumindetectionofpediatricpulmonarytuberculosis
AT wangxinfeng comparisonofbronchialbrushingandsputumindetectionofpediatricpulmonarytuberculosis
AT wangmaoshui comparisonofbronchialbrushingandsputumindetectionofpediatricpulmonarytuberculosis

Ejemplares similares