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DNAism: exploring genomic datasets on the web with Horizon Charts

BACKGROUND: Computational biologists daily face the need to explore massive amounts of genomic data. New visualization techniques can help researchers navigate and understand these big data. Horizon Charts are a relatively new visualization method that, under the right circumstances, maximizes data...

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Detalles Bibliográficos
Autores principales: Rio Deiros, David, Gibbs, Richard A., Rogers, Jeffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729118/
https://www.ncbi.nlm.nih.gov/pubmed/26819101
http://dx.doi.org/10.1186/s12859-016-0891-2
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author Rio Deiros, David
Gibbs, Richard A.
Rogers, Jeffrey
author_facet Rio Deiros, David
Gibbs, Richard A.
Rogers, Jeffrey
author_sort Rio Deiros, David
collection PubMed
description BACKGROUND: Computational biologists daily face the need to explore massive amounts of genomic data. New visualization techniques can help researchers navigate and understand these big data. Horizon Charts are a relatively new visualization method that, under the right circumstances, maximizes data density without losing graphical perception. RESULTS: Horizon Charts have been successfully applied to understand multi-metric time series data. We have adapted an existing JavaScript library (Cubism) that implements Horizon Charts for the time series domain so that it works effectively with genomic datasets. We call this new library DNAism. CONCLUSIONS: Horizon Charts can be an effective visual tool to explore complex and large genomic datasets. Researchers can use our library to leverage these techniques to extract additional insights from their own datasets. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-016-0891-2) contains supplementary material, which is available to authorized users.
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spelling pubmed-47291182016-01-28 DNAism: exploring genomic datasets on the web with Horizon Charts Rio Deiros, David Gibbs, Richard A. Rogers, Jeffrey BMC Bioinformatics Software BACKGROUND: Computational biologists daily face the need to explore massive amounts of genomic data. New visualization techniques can help researchers navigate and understand these big data. Horizon Charts are a relatively new visualization method that, under the right circumstances, maximizes data density without losing graphical perception. RESULTS: Horizon Charts have been successfully applied to understand multi-metric time series data. We have adapted an existing JavaScript library (Cubism) that implements Horizon Charts for the time series domain so that it works effectively with genomic datasets. We call this new library DNAism. CONCLUSIONS: Horizon Charts can be an effective visual tool to explore complex and large genomic datasets. Researchers can use our library to leverage these techniques to extract additional insights from their own datasets. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12859-016-0891-2) contains supplementary material, which is available to authorized users. BioMed Central 2016-01-27 /pmc/articles/PMC4729118/ /pubmed/26819101 http://dx.doi.org/10.1186/s12859-016-0891-2 Text en © Rio Deiros et al. 2016 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Software
Rio Deiros, David
Gibbs, Richard A.
Rogers, Jeffrey
DNAism: exploring genomic datasets on the web with Horizon Charts
title DNAism: exploring genomic datasets on the web with Horizon Charts
title_full DNAism: exploring genomic datasets on the web with Horizon Charts
title_fullStr DNAism: exploring genomic datasets on the web with Horizon Charts
title_full_unstemmed DNAism: exploring genomic datasets on the web with Horizon Charts
title_short DNAism: exploring genomic datasets on the web with Horizon Charts
title_sort dnaism: exploring genomic datasets on the web with horizon charts
topic Software
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729118/
https://www.ncbi.nlm.nih.gov/pubmed/26819101
http://dx.doi.org/10.1186/s12859-016-0891-2
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