Cargando…
The calcium sensor synaptotagmin 7 is required for synaptic facilitation
It has been known for over 70 years that synaptic strength is dynamically regulated in a use-dependent manner(1). At synapses with a low initial release probability, closely spaced presynaptic action potentials can result in facilitation, a short-term form of enhancement where each subsequent action...
Autores principales: | Jackman, Skyler L., Turecek, Josef, Belinsky, Justine E., Regehr, Wade G. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729191/ https://www.ncbi.nlm.nih.gov/pubmed/26738595 http://dx.doi.org/10.1038/nature16507 |
Ejemplares similares
-
Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses
por: Turecek, Josef, et al.
Publicado: (2017) -
Introduction of synaptotagmin 7 promotes facilitation at the climbing fiber to Purkinje cell synapse
por: Weyrer, Christopher, et al.
Publicado: (2021) -
The high-affinity calcium sensor synaptotagmin-7 serves multiple roles in regulated exocytosis
por: MacDougall, Daniel D., et al.
Publicado: (2018) -
Synaptotagmin-7 Is an Asynchronous Calcium Sensor for Synaptic Transmission in Neurons Expressing SNAP-23
por: Weber, Jens P., et al.
Publicado: (2014) -
The Role of Ca(V)2.1 Channel Facilitation in Synaptic Facilitation
por: Weyrer, Christopher, et al.
Publicado: (2019)