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Profilin Interaction with Actin Filament Barbed End Controls Dynamic Instability, Capping, Branching, and Motility

Cell motility and actin homeostasis depend on the control of polarized growth of actin filaments. Profilin, an abundant regulator of actin dynamics, supports filament assembly at barbed ends by binding G-actin. Here, we demonstrate how, by binding and destabilizing filament barbed ends at physiologi...

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Detalles Bibliográficos
Autores principales:	Pernier, Julien, Shekhar, Shashank, Jegou, Antoine, Guichard, Bérengère, Carlier, Marie-France
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729542/ https://www.ncbi.nlm.nih.gov/pubmed/26812019 http://dx.doi.org/10.1016/j.devcel.2015.12.024

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