Binding Site Identification and Flexible Docking of Single Stranded RNA to Proteins Using a Fragment-Based Approach

Protein-RNA docking is hampered by the high flexibility of RNA, and particularly single-stranded RNA (ssRNA). Yet, ssRNA regions typically carry the specificity of protein recognition. The lack of methodology for modeling such regions limits the accuracy of current protein-RNA docking methods. We de...

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Detalles Bibliográficos
Autores principales: Chauvot de Beauchene, Isaure, de Vries, Sjoerd J., Zacharias, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729675/
https://www.ncbi.nlm.nih.gov/pubmed/26815409
http://dx.doi.org/10.1371/journal.pcbi.1004697

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