BET Bromodomain Inhibition as a Therapeutic Strategy in Ovarian Cancer by Downregulating FoxM1

Ovarian cancer is responsible for the highest mortality among all gynecologic malignancies, and novel therapies are urgently needed to improve patient outcome. Here we performed an integrative genomic analysis and identified the bromodomain and extraterminal domain (BET) protein BRD4 as a potential...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Zhenfeng, Ma, Pengfei, Jing, Ying, Yan, Ying, Cai, Mei-Chun, Zhang, Meiying, Zhang, Shengzhe, Peng, Huixin, Ji, Zhi-Liang, Di, Wen, Gu, Zhenyu, Gao, Wei-Qiang, Zhuang, Guanglei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729770/
https://www.ncbi.nlm.nih.gov/pubmed/26877780
http://dx.doi.org/10.7150/thno.13178

Ejemplares similares

Ejemplares similares