Chemical Conjugation of Evans Blue Derivative: A Strategy to Develop Long-Acting Therapeutics through Albumin Binding

The efficacy of therapeutic drugs is highly dependent on their optimal in vivo pharmacokinetics. Albumin conjugation is considered to be one of the most effective means of protracting the short lifespan of peptides and proteins. In this study, we proposed a novel platform for developing long lasting...

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Detalles Bibliográficos
Autores principales: Chen, Haojun, Wang, Guohao, Lang, Lixin, Jacobson, Orit, Kiesewetter, Dale O., Liu, Yi, Ma, Ying, Zhang, Xianzhong, Wu, Hua, Zhu, Lei, Niu, Gang, Chen, Xiaoyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729772/
https://www.ncbi.nlm.nih.gov/pubmed/26877782
http://dx.doi.org/10.7150/thno.14322

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