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Tripartite degrons confer diversity and specificity on regulated protein degradation in the ubiquitin-proteasome system
Specific signals (degrons) regulate protein turnover mediated by the ubiquitin-proteasome system. Here we systematically analyse known degrons and propose a tripartite model comprising the following: (1) a primary degron (peptide motif) that specifies substrate recognition by cognate E3 ubiquitin li...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729826/ https://www.ncbi.nlm.nih.gov/pubmed/26732515 http://dx.doi.org/10.1038/ncomms10239 |