The “TSH Receptor Glo Assay” – A High-Throughput Detection System for Thyroid Stimulation

BACKGROUND: To identify novel small molecules against the TSH receptor, we developed a sensitive transcription-based luciferase high-throughput screening (HTS) system named the TSHR-Glo Assay (TSHR-Glo). METHODS: This assay uses double-transfected Chinese hamster ovary cells stably expressing the hu...

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Detalles Bibliográficos
Autores principales: Latif, Rauf, Lau, Zerlina, Cheung, Pamela, Felsenfeld, Dan P., Davies, Terry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729884/
https://www.ncbi.nlm.nih.gov/pubmed/26858688
http://dx.doi.org/10.3389/fendo.2016.00003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729884/
https://www.ncbi.nlm.nih.gov/pubmed/26858688
http://dx.doi.org/10.3389/fendo.2016.00003

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