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Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring

Monte Carlo tools have been long used to assist the research and development of solutions for proton therapy monitoring. The present work focuses on the prompt-gamma emission yields by comparing experimental data with the outcomes of the current version of Geant4 using all applicable proton inelasti...

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Autores principales: Pinto, Marco, Dauvergne, Denis, Freud, Nicolas, Krimmer, Jochen, Létang, Jean M., Testa, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729887/
https://www.ncbi.nlm.nih.gov/pubmed/26858937
http://dx.doi.org/10.3389/fonc.2016.00010
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author Pinto, Marco
Dauvergne, Denis
Freud, Nicolas
Krimmer, Jochen
Létang, Jean M.
Testa, Etienne
author_facet Pinto, Marco
Dauvergne, Denis
Freud, Nicolas
Krimmer, Jochen
Létang, Jean M.
Testa, Etienne
author_sort Pinto, Marco
collection PubMed
description Monte Carlo tools have been long used to assist the research and development of solutions for proton therapy monitoring. The present work focuses on the prompt-gamma emission yields by comparing experimental data with the outcomes of the current version of Geant4 using all applicable proton inelastic models. For the case in study and using the binary cascade model, it was found that Geant4 overestimates the prompt-gamma emission yields by 40.2 ± 0.3%, even though it predicts the prompt-gamma profile length of the experimental profile accurately. In addition, the default implementations of all proton inelastic models show an overestimation in the number of prompt gammas emitted. Finally, a set of built-in options and physically sound Geant4 source code changes have been tested in order to try to improve the discrepancy observed. A satisfactory agreement was found when using the QMD model with a wave packet width equal to 1.3 fm(2).
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spelling pubmed-47298872016-02-08 Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring Pinto, Marco Dauvergne, Denis Freud, Nicolas Krimmer, Jochen Létang, Jean M. Testa, Etienne Front Oncol Oncology Monte Carlo tools have been long used to assist the research and development of solutions for proton therapy monitoring. The present work focuses on the prompt-gamma emission yields by comparing experimental data with the outcomes of the current version of Geant4 using all applicable proton inelastic models. For the case in study and using the binary cascade model, it was found that Geant4 overestimates the prompt-gamma emission yields by 40.2 ± 0.3%, even though it predicts the prompt-gamma profile length of the experimental profile accurately. In addition, the default implementations of all proton inelastic models show an overestimation in the number of prompt gammas emitted. Finally, a set of built-in options and physically sound Geant4 source code changes have been tested in order to try to improve the discrepancy observed. A satisfactory agreement was found when using the QMD model with a wave packet width equal to 1.3 fm(2). Frontiers Media S.A. 2016-01-28 /pmc/articles/PMC4729887/ /pubmed/26858937 http://dx.doi.org/10.3389/fonc.2016.00010 Text en Copyright © 2016 Pinto, Dauvergne, Freud, Krimmer, Létang and Testa. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Pinto, Marco
Dauvergne, Denis
Freud, Nicolas
Krimmer, Jochen
Létang, Jean M.
Testa, Etienne
Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title_full Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title_fullStr Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title_full_unstemmed Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title_short Assessment of Geant4 Prompt-Gamma Emission Yields in the Context of Proton Therapy Monitoring
title_sort assessment of geant4 prompt-gamma emission yields in the context of proton therapy monitoring
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729887/
https://www.ncbi.nlm.nih.gov/pubmed/26858937
http://dx.doi.org/10.3389/fonc.2016.00010
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