Cargando…

Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination

Aging is associated with hyporesponse to vaccination, whose mechanisms remain unclear. In this study hepatitis B virus (HBV)-naive older adults received three vaccines, including one against HBV. Here we show, using transcriptional and cytometric profiling of whole blood collected before vaccination...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fourati, Slim, Cristescu, Razvan, Loboda, Andrey, Talla, Aarthi, Filali, Ali, Railkar, Radha, Schaeffer, Andrea K., Favre, David, Gagnon, Dominic, Peretz, Yoav, Wang, I-Ming, Beals, Chan R., Casimiro, Danilo R., Carayannopoulos, Leonidas N., Sékaly, Rafick-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729923/ https://www.ncbi.nlm.nih.gov/pubmed/26742691 http://dx.doi.org/10.1038/ncomms10369

Ejemplares similares

The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
por: Sekaly, Rafick-Pierre
Publicado: (2008)

Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine
por: Fourati, Slim, et al.
Publicado: (2019)

Transcriptional profiling of vaccine‐induced immune responses in humans and non‐human primates
por: Wang, I‐Ming, et al.
Publicado: (2012)

A systems framework for vaccine design
por: Mooney, Michael, et al.
Publicado: (2013)

Hypotonic-hyporesponsive Episodes After Diphtheria, Tetanus and Acellular Pertussis Vaccination
por: Hansen, John, et al.
Publicado: (2021)

Carrier-Induced Hyporesponsiveness to Pneumococcal Conjugate Vaccines: Unraveling the Influence of Serotypes, Timing, and Previous Vaccine Dose
por: Dagan, Ron, et al.
Publicado: (2020)

Third dose of COVID-19 mRNA vaccine appears to overcome vaccine hyporesponsiveness in patients with cirrhosis
por: John, Binu V., et al.
Publicado: (2022)

Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate
por: Vaccari, Monica, et al.
Publicado: (2019)

Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination
por: Fourati, Slim, et al.
Publicado: (2022)

Translating known drivers of COVID-19 disease severity to design better SARS-CoV-2 vaccines
por: Pelletier, Adam N, et al.
Publicado: (2022)

27. Immunologic Hyporesponsiveness with Subsequent Dosing of Meningococcal Vaccines: Re-Evaluating the Current Paradigm
por: Findlow, Jamie, et al.
Publicado: (2021)

Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation
por: Pandiyan, Pushpa, et al.
Publicado: (2016)

Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses
por: Muir, Roshell, et al.
Publicado: (2023)

Transcriptional and Immunologic Correlates of Response to Pandemic Influenza Vaccine in Aviremic, HIV-Infected Children
por: de Armas, Lesley R., et al.
Publicado: (2021)

Immunogenicity of an Additional mRNA-1273 SARS-CoV-2 Vaccination in People With HIV With Hyporesponse After Primary Vaccination
por: Jongkees, Marlou J, et al.
Publicado: (2022)

High-dimensional analysis of the aging immune system: Verification of age-associated differences in immune signaling responses in healthy donors
por: Longo, Diane M, et al.
Publicado: (2014)

Recent advances in understanding and diagnosing hepatitis B virus infection
por: Fourati, Slim, et al.
Publicado: (2016)

Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines
por: Rosenbloom, Daniel I. S., et al.
Publicado: (2023)

Waning effectiveness of the third dose of the BNT162b2 mRNA COVID-19 vaccine
por: Patalon, Tal, et al.
Publicado: (2022)

Early Clinical Detection of Pharmacologic Response in Insulin Action in a Nondiabetic Insulin-Resistant Population
por: Shankar, Sudha S., et al.
Publicado: (2015)

Pneumococcal conjugate vaccine induced IgG and nasopharyngeal carriage of pneumococci: Hyporesponsiveness and immune correlates of protection for carriage
por: Ojal, John, et al.
Publicado: (2017)

STAT3 governs hyporesponsiveness and granzyme B-dependent suppressive capacity in human CD4(+) T cells
por: Schmetterer, Klaus G., et al.
Publicado: (2015)

Ionomycin Treatment Renders NK Cells Hyporesponsive
por: Romera-Cárdenas, Gema, et al.
Publicado: (2016)

An Exploratory Study of Daprodustat in Erythropoietin-Hyporesponsive Subjects
por: Cizman, Borut, et al.
Publicado: (2018)

NK Cell Hyporesponsiveness: More Is Not Always Better
por: Frutoso, Marie, et al.
Publicado: (2019)

Immunological hyporesponsiveness in tuberculosis: The role of mycobacterial glycolipids
por: Correia-Neves, Margarida, et al.
Publicado: (2022)

Healthy elderly Singaporeans show no age-related humoral hyporesponsiveness nor diminished plasmablast generation in response to influenza vaccine
por: Camous, Xavier, et al.
Publicado: (2018)

Short Vi-polysaccharide abrogates T-independent immune response and hyporesponsiveness elicited by long Vi-CRM(197) conjugate vaccine
por: Micoli, Francesca, et al.
Publicado: (2020)

Vaccine Hyporesponse Induced by Individual Antibiotic Treatment in Mice and Non-Human Primates Is Diminished upon Recovery of the Gut Microbiome
por: Swaminathan, Gokul, et al.
Publicado: (2021)

Development of a TLR7/8 agonist adjuvant formulation to overcome early life hyporesponsiveness to DTaP vaccination
por: Dowling, David J., et al.
Publicado: (2022)

The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination
por: Tomalka, Jeffrey Alan, et al.
Publicado: (2021)

Therapeutic Potential of Hyporesponsive CD4(+) T Cells in Autoimmunity
por: Maggi, Jaxaira, et al.
Publicado: (2015)

Factors Influencing Aspirin Hyporesponsiveness in Elderly Chinese Patients
por: Ou, Wei mei, et al.
Publicado: (2019)

Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4(+) T Cells
por: Kulpa, Deanna A., et al.
Publicado: (2019)

Endogenous Serum IgG Antibodies to Clostridium difficile Toxin B Are Associated with Protection against C. difficile Infection Recurrence
por: Kelly, Ciaran P, et al.
Publicado: (2017)

Case Report: Evolution of Humoral and Cellular Immunity in Two COVID-19 Breakthrough Infections After BNT162b2 Vaccine
por: Gallais, Floriane, et al.
Publicado: (2022)

Human newborn bacille Calmette–Guérin vaccination and risk of tuberculosis disease: a case-control study
por: Fletcher, Helen A., et al.
Publicado: (2016)

A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology
por: Liu, Jie, et al.
Publicado: (2016)

Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy
por: Kropf, Pascale, et al.
Publicado: (2007)

Aspirin and clopidogrel hyporesponsiveness and nonresponsiveness in patients with coronary artery stenting
por: Sharma, Rakesh K, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_3rmg2h56frccl717juff3qs7o3