Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from PPAT support the directed migration of prostate cancer cells and that this event is strongly promoted by obesity. This p...

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Detalles Bibliográficos
Autores principales: Laurent, Victor, Guérard, Adrien, Mazerolles, Catherine, Le Gonidec, Sophie, Toulet, Aurélie, Nieto, Laurence, Zaidi, Falek, Majed, Bilal, Garandeau, David, Socrier, Youri, Golzio, Muriel, Cadoudal, Thomas, Chaoui, Karima, Dray, Cedric, Monsarrat, Bernard, Schiltz, Odile, Wang, Yuan Yuan, Couderc, Bettina, Valet, Philippe, Malavaud, Bernard, Muller, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729927/
https://www.ncbi.nlm.nih.gov/pubmed/26756352
http://dx.doi.org/10.1038/ncomms10230

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