Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2–JNK signalling in breast cancer

The non-canonical Wnt/planar cell polarity (Wnt/PCP) pathway plays a crucial role in embryonic development. Recent work has linked defects of this pathway to breast cancer aggressiveness and proposed Wnt/PCP signalling as a therapeutic target. Here we show that the archetypal Wnt/PCP protein VANGL2...

Descripción completa

Detalles Bibliográficos
Autores principales: Puvirajesinghe, Tania M., Bertucci, François, Jain, Ashish, Scerbo, Pierluigi, Belotti, Edwige, Audebert, Stéphane, Sebbagh, Michael, Lopez, Marc, Brech, Andreas, Finetti, Pascal, Charafe-Jauffret, Emmanuelle, Chaffanet, Max, Castellano, Rémy, Restouin, Audrey, Marchetto, Sylvie, Collette, Yves, Gonçalvès, Anthony, Macara, Ian, Birnbaum, Daniel, Kodjabachian, Laurent, Johansen, Terje, Borg, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729931/
https://www.ncbi.nlm.nih.gov/pubmed/26754771
http://dx.doi.org/10.1038/ncomms10318

Ejemplares similares

Ejemplares similares