Cargando…
Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease
The etiology of idiopathic Parkinson's disease (idPD) remains enigmatic despite recent successes in identification of genes (PARKs) that underlie familial PD. To find new keys to this incurable neurodegenerative disorder we focused on the poorly understood PARK14 disease locus (Pla2g6 gene) and...
Autores principales: | Zhou, Qingde, Yen, Allen, Rymarczyk, Grzegorz, Asai, Hirohide, Trengrove, Chelsea, Aziz, Nadine, Kirber, Michael T., Mostoslavsky, Gustavo, Ikezu, Tsuneya, Wolozin, Benjamin, Bolotina, Victoria M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729940/ https://www.ncbi.nlm.nih.gov/pubmed/26755131 http://dx.doi.org/10.1038/ncomms10332 |
Ejemplares similares
-
Syk and Yea Shall Find
por: Wolozin, Benjamin, et al.
Publicado: (2015) -
Corrigendum to “Syk and ye shall find” [EBioMedicine 2 (11) (2015) 190-1591]
por: Wolozin, Benjamin, et al.
Publicado: (2016) -
Crohn’s and Parkinson’s Disease-Associated LRRK2 Mutations Alter Type II Interferon Responses in Human CD14(+) Blood Monocytes Ex Vivo
por: Ikezu, Tsuneya, et al.
Publicado: (2020) -
Interaction of LRRK2 with kinase and GTPase signaling cascades
por: Boon, Joon Y., et al.
Publicado: (2014) -
Tau-tubulin kinase
por: Ikezu, Seiko, et al.
Publicado: (2014)