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The Atg1–kinase complex tethers Atg9-vesicles to initiate autophagy
Autophagosomes are double-membrane vesicles that sequester cytoplasmic material for lysosomal degradation. Their biogenesis is initiated by recruitment of Atg9-vesicles to the phagophore assembly site. This process depends on the regulated activation of the Atg1–kinase complex. However, the underlyi...
Autores principales: | Rao, Yijian, Perna, Marco G., Hofmann, Benjamin, Beier, Viola, Wollert, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4729957/ https://www.ncbi.nlm.nih.gov/pubmed/26753620 http://dx.doi.org/10.1038/ncomms10338 |
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