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Overlapping signatures of chronic pain in the DNA methylation landscape of prefrontal cortex and peripheral T cells

We tested the hypothesis that epigenetic mechanisms in the brain and the immune system are associated with chronic pain. Genome-wide DNA methylation assessed in 9 months post nerve-injury (SNI) and Sham rats, in the prefrontal cortex (PFC) as well as in T cells revealed a vast difference in the DNA...

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Detalles Bibliográficos
Autores principales:	Massart, Renaud, Dymov, Sergiy, Millecamps, Magali, Suderman, Matthew, Gregoire, Stephanie, Koenigs, Kevin, Alvarado, Sebastian, Tajerian, Maral, Stone, Laura S., Szyf, Moshe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730199/ https://www.ncbi.nlm.nih.gov/pubmed/26817950 http://dx.doi.org/10.1038/srep19615

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