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GTPase domain driven dimerization of SEPT7 is dispensable for the critical role of septins in fibroblast cytokinesis

Septin 7 (SEPT7) has been described to be essential for successful completion of cytokinesis in mouse fibroblasts, and Sept7-deficiency in fibroblasts constitutively results in multinucleated cells which stop proliferation. Using Sept7(flox/flox)fibroblasts we generated a cellular system, where the...

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Detalles Bibliográficos
Autores principales:	Abbey, Megha, Hakim, Cosima, Anand, Roopsee, Lafera, Juri, Schambach, Axel, Kispert, Andreas, Taft, Manuel H., Kaever, Volkhard, Kotlyarov, Alexey, Gaestel, Matthias, Menon, Manoj B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730212/ https://www.ncbi.nlm.nih.gov/pubmed/26818767 http://dx.doi.org/10.1038/srep20007

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