Cargando…

Does Variation of the Inter-Domain Linker Sequence Modulate the Metal Binding Behaviour of Helix pomatia Cd-Metallothionein?

Snail metallothioneins (MTs) constitute an ideal model to study structure/function relationships in these metal-binding polypeptides. Helix pomatia harbours three MT isoforms: the highly specific CdMT and CuMT, and an unspecific Cd/CuMT, which represent paralogous proteins with extremely different m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gil-Moreno, Selene, Jiménez-Martí, Elena, Palacios, Òscar, Zerbe, Oliver, Dallinger, Reinhard, Capdevila, Mercè, Atrian, Sílvia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730253/ https://www.ncbi.nlm.nih.gov/pubmed/26703589 http://dx.doi.org/10.3390/ijms17010006

Ejemplares similares

Analysis of Metal-Binding Features of the Wild Type and Two Domain-Truncated Mutant Variants of Littorina littorea Metallothionein Reveals Its Cd-Specific Character
por: Palacios, Òscar, et al.
Publicado: (2017)

Evolution of Cd(2+) and Cu(+) binding in Helix pomatia metallothioneins
por: Valsecchi, Renato, et al.
Publicado: (2023)

Biomphalaria glabrata Metallothionein: Lacking Metal Specificity of the Protein and Missing Gene Upregulation Suggest Metal Sequestration by Exchange Instead of through Selective Binding
por: Niederwanger, Michael, et al.
Publicado: (2017)

Shaping mechanisms of metal specificity in a family of metazoan metallothioneins: evolutionary differentiation of mollusc metallothioneins
por: Palacios, Òscar, et al.
Publicado: (2011)

The Fungus Tremella mesenterica Encodes the Longest Metallothionein Currently Known: Gene, Protein and Metal Binding Characterization
por: Iturbe-Espinoza, Paul, et al.
Publicado: (2016)

The Zn- or Cu-Thionein Character of a Metallothionein Determines Its Metal Load When Synthesized in Physiological (Metal-Unsupplemented) Conditions
por: Capdevila, Mercè, et al.
Publicado: (2010)

Hints for Metal-Preference Protein Sequence Determinants: Different Metal Binding Features of the Five Tetrahymena thermophila Metallothioneins
por: Espart, Anna, et al.
Publicado: (2015)

Metal Dealing at the Origin of the Chordata Phylum: The Metallothionein System and Metal Overload Response in Amphioxus
por: Guirola, Maria, et al.
Publicado: (2012)

Helix pomatia and prognosis of breast cancer.
por: Walker, R. A.
Publicado: (1993)

A de novo evolved domain improves the cadmium detoxification capacity of limpet metallothioneins
por: García-Risco, Mario, et al.
Publicado: (2023)

Two Unconventional Metallothioneins in the Apple Snail Pomacea bridgesii Have Lost Their Metal Specificity during Adaptation to Freshwater Habitats
por: García-Risco, Mario, et al.
Publicado: (2020)

The Modular Architecture of Metallothioneins Facilitates Domain Rearrangements and Contributes to Their Evolvability in Metal-Accumulating Mollusks
por: Calatayud, Sara, et al.
Publicado: (2022)

Modularity in Protein Evolution: Modular Organization and De Novo Domain Evolution in Mollusk Metallothioneins
por: Calatayud, Sara, et al.
Publicado: (2020)

Metal-Specificity Divergence between Metallothioneins of Nerita peloronta (Neritimorpha, Gastropoda) Sets the Starting Point for a Novel Chemical MT Classification Proposal
por: García-Risco, Mario, et al.
Publicado: (2021)

Binding of aberrant glycoproteins recognizable by Helix pomatia agglutinin in adrenal cancers
por: Parameswaran, R., et al.
Publicado: (2018)

The sea urchin metallothionein system: Comparative evaluation of the SpMTA and SpMTB metal-binding preferences()
por: Tomas, Mireia, et al.
Publicado: (2013)

Modular Evolution and Population Variability of Oikopleura dioica Metallothioneins
por: Calatayud, Sara, et al.
Publicado: (2021)

An Electron Microscope Study of the Cells Lining the Small Blood Vessels of Helix pomatia Linn
por: Threadgold, L. T., et al.
Publicado: (1958)

Prognostic value of Helix pomatia in breast cancer. International (Ludwig) Breast Cancer Study Group.
Publicado: (1993)

Electron Paramagnetic Resonance Studies of Irradiated Grape Snails (Helix pomatia) and Investigation of Biophysical Parameters
por: Nasibova, Aygun, et al.
Publicado: (2023)

Helix pomatia agglutinin binding in human tumour cell lines: correlation with pulmonary metastases in nude mice.
por: Kjønniksen, I., et al.
Publicado: (1994)

Prognostic significance of Helix pomatia lectin and c-erbB-2 oncoprotein in human breast cancer.
por: Thomas, M., et al.
Publicado: (1993)

Identification of O-Linked Glycoproteins Binding to the Lectin Helix pomatia Agglutinin as Markers of Metastatic Colorectal Cancer
por: Peiris, Diluka, et al.
Publicado: (2015)

Fluorescence Imaging of Streptococcus pneumoniae with the Helix pomatia agglutinin (HPA) As a Potential, Rapid Diagnostic Tool
por: Domenech, Mirian, et al.
Publicado: (2017)

The T/Tn-Specific Helix pomatia Lectin Induces Cell Death in Lymphoma Cells Negative for T/Tn Antigens
por: Simplicien, Mathias, et al.
Publicado: (2021)

The AMP deaminase of the mollusk Helix pomatia is an unexpected member of the adenosine deaminase-related growth factor (ADGF) family
por: Tzertzinis, George, et al.
Publicado: (2023)

Tunicates Illuminate the Enigmatic Evolution of Chordate Metallothioneins by Gene Gains and Losses, Independent Modular Expansions, and Functional Convergences
por: Calatayud, Sara, et al.
Publicado: (2021)

Accumulation of Cadmium in and Its Effect on the Midgut Gland of Terrestrial Snail Helix pomatia L. from Urban Areas in Poland
por: Włostowski, Tadeusz, et al.
Publicado: (2014)

Further analysis of predictive value of Helix pomatia lectin binding to primary breast cancer for axillary and internal mammary lymph node metastases.
por: Noguchi, M., et al.
Publicado: (1993)

Intermediate filaments in non-neuronal cells of invertebrates: isolation and biochemical characterization of intermediate filaments from the esophageal epithelium of the mollusc Helix pomatia
Publicado: (1985)

Populations of herpes simplex virus glycoprotein gC with and without affinity for the N-acetyl-galactosamine specific lectin ofHelix pomatia
por: Olofsson, S., et al.
Publicado: (1983)

Metallothionein gene activation in the earthworm (Lumbricus rubellus)
por: Höckner, M., et al.
Publicado: (2015)

Physiological, Diurnal and Stress-Related Variability of Cadmium-Metallothionein Gene Expression in Land Snails
por: Pedrini-Martha, Veronika, et al.
Publicado: (2016)

Nicotinic Acetylcholine Receptors Containing the α7-Like Subunit Mediate Contractions of Muscles Responsible for Space Positioning of the Snail, Helix pomatia L. Tentacle
por: Kiss, Tibor, et al.
Publicado: (2014)

Responsiveness of metallothionein and hemocyanin genes to cadmium and copper exposure in the garden snail Cornu aspersum
por: Pedrini‐Martha, Veronika, et al.
Publicado: (2020)

Cadmium Accumulation and Pathological Alterations in the Midgut Gland of Terrestrial Snail Helix pomatia L. from a Zinc Smelter Area: Role of Soil pH
por: Włostowski, Tadeusz, et al.
Publicado: (2016)

Cadmium Uptake, MT Gene Activation and Structure of Large-Sized Multi-Domain Metallothioneins in the Terrestrial Door Snail Alinda biplicata (Gastropoda, Clausiliidae)
por: Pedrini-Martha, Veronika, et al.
Publicado: (2020)

Cadmium Pathways in Snails Follow a Complementary Strategy between Metallothionein Detoxification and Auxiliary Inactivation by Phytochelatins
por: Dvorak, Martin, et al.
Publicado: (2019)

Challenging the Metallothionein (MT) Gene of Biomphalaria glabrata: Unexpected Response Patterns Due to Cadmium Exposure and Temperature Stress
por: Niederwanger, Michael, et al.
Publicado: (2017)

Differential Expression of Metallothionein Isoforms in Terrestrial Snail Embryos Reflects Early Life Stage Adaptation to Metal Stress
por: Baurand, Pierre-Emmanuel, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ac9r49jh5du2bu4hv9s8uo1fth