Effect of Chromatin Structure on the Extent and Distribution of DNA Double Strand Breaks Produced by Ionizing Radiation; Comparative Study of hESC and Differentiated Cells Lines

Chromatin structure affects the extent of DNA damage and repair. Thus, it has been shown that heterochromatin is more protective against DNA double strand breaks (DSB) formation by ionizing radiation (IR); and that DNA DSB repair may proceed differently in hetero- and euchromatin regions. Human embr...

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Detalles Bibliográficos
Autores principales: Venkatesh, Priyanka, Panyutin, Irina V., Remeeva, Evgenia, Neumann, Ronald D., Panyutin, Igor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730303/
https://www.ncbi.nlm.nih.gov/pubmed/26729112
http://dx.doi.org/10.3390/ijms17010058

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