Cargando…

Insights into Mechanisms of Chronic Neurodegeneration

Chronic neurodegenerative diseases such as Alzheimer’s disease (AD), Parkinson’s disease (PD), and prion diseases are characterised by the accumulation of abnormal conformers of a host encoded protein in the central nervous system. The process leading to neurodegeneration is still poorly defined and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Diack, Abigail B., Alibhai, James D., Barron, Rona, Bradford, Barry, Piccardo, Pedro, Manson, Jean C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730326/ https://www.ncbi.nlm.nih.gov/pubmed/26771599 http://dx.doi.org/10.3390/ijms17010082

Ejemplares similares

Disease-associated protein seeding suggests a dissociation between misfolded protein accumulation and neurodegeneration in prion disease
por: Alibhai, James, et al.
Publicado: (2017)

Distribution of Misfolded Prion Protein Seeding Activity Alone Does Not Predict Regions of Neurodegeneration
por: Alibhai, James, et al.
Publicado: (2016)

Host PrP Glycosylation: A Major Factor Determining the Outcome of Prion Infection
por: Tuzi, Nadia L, et al.
Publicado: (2008)

The Glycosylation Status of PrP(C) Is a Key Factor in Determining Transmissible Spongiform Encephalopathy Transmission between Species
por: Wiseman, Frances K., et al.
Publicado: (2015)

Ablation of Prion Protein in Wild Type Human Amyloid Precursor Protein (APP) Transgenic Mice Does Not Alter The Proteolysis of APP, Levels of Amyloid-β or Pathologic Phenotype
por: Whitehouse, Isobel J., et al.
Publicado: (2016)

Public health risks from subclinical variant CJD
por: Diack, Abigail B., et al.
Publicado: (2017)

Defining the Microglia Response during the Time Course of Chronic Neurodegeneration
por: Vincenti, James E., et al.
Publicado: (2016)

Variable tau accumulation in murine models with abnormal prion protein deposits
por: Piccardo, Pedro, et al.
Publicado: (2017)

Variably Protease-Sensitive Prionopathy, a Unique Prion Variant with Inefficient Transmission Properties
por: Diack, Abigail B., et al.
Publicado: (2014)

Constant Transmission Properties of Variant Creutzfeldt-Jakob Disease in 5 Countries
por: Diack, Abigail B., et al.
Publicado: (2012)

Variant CJD: 18 years of research and surveillance
por: Diack, Abigail B, et al.
Publicado: (2014)

Novel insights into the mechanism of reactive oxygen species-mediated neurodegeneration
por: Wakatsuki, Shuji, et al.
Publicado: (2022)

Prion infectivity in the spleen of a PRNP heterozygous individual with subclinical variant Creutzfeldt–Jakob disease
por: Bishop, Matthew T., et al.
Publicado: (2013)

An Insight into Cellular and Molecular Mechanisms Underlying the Pathogenesis of Neurodegeneration in Alzheimer’s Disease
por: Ratan, Yashumati, et al.
Publicado: (2023)

Lysosomal acidification dysfunction in microglia: an emerging pathogenic mechanism of neuroinflammation and neurodegeneration
por: Quick, Joseph D., et al.
Publicado: (2023)

Review: Insights into molecular mechanisms of disease in neurodegeneration with brain iron accumulation: unifying theories
por: Arber, C. E., et al.
Publicado: (2015)

Variant Creutzfeldt-Jakob disease strain is identical in individuals of two PRNP codon 129 genotypes
por: Diack, Abigail B, et al.
Publicado: (2019)

No Adaptation of the Prion Strain in a Heterozygous Case of Variant Creutzfeldt-Jakob Disease
por: Boyle, Aileen, et al.
Publicado: (2020)

Role of neuroinflammation in neurodegeneration: new insights
por: McManus, Róisín M., et al.
Publicado: (2017)

New Insights into Multiple Sclerosis Mechanisms: Lipids on the Track to Control Inflammation and Neurodegeneration
por: Podbielska, Maria, et al.
Publicado: (2021)

PrP aggregation can be seeded by pre-formed recombinant PrP amyloid fibrils without the replication of infectious prions
por: Barron, Rona M., et al.
Publicado: (2016)

Current Insights on Neurodegeneration by the Italian Proteomics Community
por: Alberio, Tiziana, et al.
Publicado: (2022)

Similarities of Variant Creutzfeldt-Jakob Disease Strain in Mother and Son in Spain to UK Reference Case
por: Diack, Abigail B., et al.
Publicado: (2017)

RNA-binding proteins in neurodegeneration: mechanisms in aggregate
por: Conlon, Erin G., et al.
Publicado: (2017)

Drosophila models reveal novel insights into mechanisms underlying neurodegeneration
por: Mohan, Ryan D, et al.
Publicado: (2014)

Increased susceptibility of transgenic mice expressing human PrP to experimental sheep bovine spongiform encephalopathy is not due to increased agent titre in sheep brain tissue
por: Plinston, Chris, et al.
Publicado: (2014)

Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates
por: Phadwal, Kanchan, et al.
Publicado: (2018)

Insights into neurodegeneration from electron microscopy studies
por: Crowther, R. Anthony
Publicado: (2021)

Insights on altered mitochondrial function and dynamics in the pathogenesis of neurodegeneration
por: McInnes, Joseph
Publicado: (2013)

Possible Neuroprotective Mechanisms of Physical Exercise in Neurodegeneration
por: Mahalakshmi, B., et al.
Publicado: (2020)

Mechanism of Oxidative Stress in Neurodegeneration
por: Gandhi, Sonia, et al.
Publicado: (2012)

MicroRNAs and Molecular Mechanisms of Neurodegeneration
por: Bicchi, Ilaria, et al.
Publicado: (2013)

Intersection between Redox Homeostasis and Autophagy: Valuable Insights into Neurodegeneration
por: Park, Hyungsun, et al.
Publicado: (2021)

Recent Insight into the Role of Sphingosine-1-Phosphate Lyase in Neurodegeneration
por: Wieczorek, Iga, et al.
Publicado: (2023)

Perspective: Treatment for Disease Modification in Chronic Neurodegeneration
por: Müller, Thomas, et al.
Publicado: (2021)

New Insights into the Neurodegeneration Mechanisms Underlying Riboflavin Transporter Deficiency (RTD): Involvement of Energy Dysmetabolism and Cytoskeletal Derangement
por: Colasuonno, Fiorella, et al.
Publicado: (2022)

Molecular Mechanisms of Neurodegeneration in Spinal Muscular Atrophy
por: Ahmad, Saif, et al.
Publicado: (2016)

Basic mechanisms of neurodegeneration: a critical update
por: Jellinger, Kurt A
Publicado: (2010)

Nature of Tau-Associated Neurodegeneration and the Molecular Mechanisms
por: Yang, Ying, et al.
Publicado: (2018)

Bioactive Polyphenols and Neuromodulation: Molecular Mechanisms in Neurodegeneration
por: Di Meo, Francesco, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_msaut89qu6eghh1f4g9cv38vmf