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Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730346/ https://www.ncbi.nlm.nih.gov/pubmed/26784175 http://dx.doi.org/10.3390/ijms17010104 |
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author | Lim, Lucy Yan, Fangzhi Bach, Stephen Pihakari, Katianna Klein, David |
author_facet | Lim, Lucy Yan, Fangzhi Bach, Stephen Pihakari, Katianna Klein, David |
author_sort | Lim, Lucy |
collection | PubMed |
description | Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now have a tool for difficult and complex environmental analyses. Two features of FTMS are responsible for changing the face of how complex analyses are accomplished. First is the ability to quickly and with high mass accuracy determine the presence of unknown chemical residues in samples. For years, the field has been limited by mass spectrometric methods that were based on knowing what compounds of interest were. Secondly, by utilizing the high resolution capabilities coupled with the low detection limits of FTMS, analysts also could dilute the sample sufficiently to minimize the ionization changes from varied matrices. |
format | Online Article Text |
id | pubmed-4730346 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-47303462016-02-11 Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses Lim, Lucy Yan, Fangzhi Bach, Stephen Pihakari, Katianna Klein, David Int J Mol Sci Review Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now have a tool for difficult and complex environmental analyses. Two features of FTMS are responsible for changing the face of how complex analyses are accomplished. First is the ability to quickly and with high mass accuracy determine the presence of unknown chemical residues in samples. For years, the field has been limited by mass spectrometric methods that were based on knowing what compounds of interest were. Secondly, by utilizing the high resolution capabilities coupled with the low detection limits of FTMS, analysts also could dilute the sample sufficiently to minimize the ionization changes from varied matrices. MDPI 2016-01-14 /pmc/articles/PMC4730346/ /pubmed/26784175 http://dx.doi.org/10.3390/ijms17010104 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Lim, Lucy Yan, Fangzhi Bach, Stephen Pihakari, Katianna Klein, David Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title | Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title_full | Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title_fullStr | Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title_full_unstemmed | Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title_short | Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses |
title_sort | fourier transform mass spectrometry: the transformation of modern environmental analyses |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730346/ https://www.ncbi.nlm.nih.gov/pubmed/26784175 http://dx.doi.org/10.3390/ijms17010104 |
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