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Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses

Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now...

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Detalles Bibliográficos
Autores principales: Lim, Lucy, Yan, Fangzhi, Bach, Stephen, Pihakari, Katianna, Klein, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730346/
https://www.ncbi.nlm.nih.gov/pubmed/26784175
http://dx.doi.org/10.3390/ijms17010104
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author Lim, Lucy
Yan, Fangzhi
Bach, Stephen
Pihakari, Katianna
Klein, David
author_facet Lim, Lucy
Yan, Fangzhi
Bach, Stephen
Pihakari, Katianna
Klein, David
author_sort Lim, Lucy
collection PubMed
description Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now have a tool for difficult and complex environmental analyses. Two features of FTMS are responsible for changing the face of how complex analyses are accomplished. First is the ability to quickly and with high mass accuracy determine the presence of unknown chemical residues in samples. For years, the field has been limited by mass spectrometric methods that were based on knowing what compounds of interest were. Secondly, by utilizing the high resolution capabilities coupled with the low detection limits of FTMS, analysts also could dilute the sample sufficiently to minimize the ionization changes from varied matrices.
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spelling pubmed-47303462016-02-11 Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses Lim, Lucy Yan, Fangzhi Bach, Stephen Pihakari, Katianna Klein, David Int J Mol Sci Review Unknown compounds in environmental samples are difficult to identify using standard mass spectrometric methods. Fourier transform mass spectrometry (FTMS) has revolutionized how environmental analyses are performed. With its unsurpassed mass accuracy, high resolution and sensitivity, researchers now have a tool for difficult and complex environmental analyses. Two features of FTMS are responsible for changing the face of how complex analyses are accomplished. First is the ability to quickly and with high mass accuracy determine the presence of unknown chemical residues in samples. For years, the field has been limited by mass spectrometric methods that were based on knowing what compounds of interest were. Secondly, by utilizing the high resolution capabilities coupled with the low detection limits of FTMS, analysts also could dilute the sample sufficiently to minimize the ionization changes from varied matrices. MDPI 2016-01-14 /pmc/articles/PMC4730346/ /pubmed/26784175 http://dx.doi.org/10.3390/ijms17010104 Text en © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Lim, Lucy
Yan, Fangzhi
Bach, Stephen
Pihakari, Katianna
Klein, David
Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title_full Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title_fullStr Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title_full_unstemmed Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title_short Fourier Transform Mass Spectrometry: The Transformation of Modern Environmental Analyses
title_sort fourier transform mass spectrometry: the transformation of modern environmental analyses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730346/
https://www.ncbi.nlm.nih.gov/pubmed/26784175
http://dx.doi.org/10.3390/ijms17010104
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