Statin Therapy and the Development of Cerebral Amyloid Angiopathy—A Rodent in Vivo Approach

Background: Cerebral amyloid angiopathy (CAA) is characterized by vascular deposition of amyloid β (Aβ) with a higher incidence of cerebral microbleeds (cMBs) and spontaneous hemorrhage. Since statins are known for their benefit in vascular disease we tested for the effect on CAA. Methods: APP23-tra...

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Detalles Bibliográficos
Autores principales: Reuter, Björn, Venus, Alexander, Grudzenski, Saskia, Heiler, Patrick, Schad, Lothar, Staufenbiel, Matthias, Hennerici, Michael G., Fatar, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730367/
https://www.ncbi.nlm.nih.gov/pubmed/26797603
http://dx.doi.org/10.3390/ijms17010126

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