Cargando…

The Clinical Significance of Phosphorylated Heat Shock Protein 27 (HSPB1) in Pancreatic Cancer

Pancreatic cancer is one of most aggressive forms of cancer. After clinical detection it exhibits fast metastatic growth. Heat shock protein 27 (HSP27; HSPB1) has been characterized as a molecular chaperone which modifies the structures and functions of other proteins in cells when they are exposed...

Descripción completa

Detalles Bibliográficos
Autores principales:	Okuno, Mitsuru, Adachi, Seiji, Kozawa, Osamu, Shimizu, Masahito, Yasuda, Ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2016
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730376/ https://www.ncbi.nlm.nih.gov/pubmed/26805817 http://dx.doi.org/10.3390/ijms17010137

Ejemplares similares

The significance of phosphorylated heat shock protein 27 on the prognosis of pancreatic cancer
por: Okuno, Mitsuru, et al.
Publicado: (2016)

Phosphorylated Heat Shock Protein 20 (HSPB6) Regulates Transforming Growth Factor-α-Induced Migration and Invasion of Hepatocellular Carcinoma Cells
por: Matsushima-Nishiwaki, Rie, et al.
Publicado: (2016)

Heat shock protein 27 (HSPB1) suppresses the PDGF-BB-induced migration of osteoblasts
por: Kainuma, Shingo, et al.
Publicado: (2017)

Heat-Shock Protein 27 (HSPB1) Is Upregulated and Phosphorylated in Human Platelets during ST-Elevation Myocardial Infarction
por: Kraemer, Bjoern F., et al.
Publicado: (2019)

Direct Association of Heat Shock Protein 20 (HSPB6) with Phosphoinositide 3-kinase (PI3K) in Human Hepatocellular Carcinoma: Regulation of the PI3K Activity
por: Matsushima-Nishiwaki, Rie, et al.
Publicado: (2013)

Release of Phosphorylated HSP27 (HSPB1) from Platelets Is Accompanied with the Acceleration of Aggregation in Diabetic Patients
por: Tokuda, Haruhiko, et al.
Publicado: (2015)

Significance of unphosphorylated and phosphorylated heat shock protein 27 as a prognostic biomarker in pancreatic ductal adenocarcinoma
por: Drexler, Richard, et al.
Publicado: (2020)

Heat‐shock protein 27 (HSP27, HSPB1) is synthetic lethal to cells with oncogenic activation of MET, EGFR and BRAF
por: Konda, John D., et al.
Publicado: (2017)

Phosphorylation of the small heat shock protein HspB1 regulates cytoskeletal recruitment and cell motility
por: Hoffman, Laura M., et al.
Publicado: (2022)

Thrombin Receptor-Activating Protein (TRAP)-Activated Akt Is Involved in the Release of Phosphorylated-HSP27 (HSPB1) from Platelets in DM Patients
por: Tokuda, Haruhiko, et al.
Publicado: (2016)

Targeting heat shock protein 27 (HspB1) interferes with bone metastasis and tumour formation in vivo
por: Gibert, B, et al.
Publicado: (2012)

Knock Down of Heat Shock Protein 27 (HspB1) Induces Degradation of Several Putative Client Proteins
por: Gibert, Benjamin, et al.
Publicado: (2012)

Evaluation of the Small Heat Shock Protein Family Members HSPB2 and HSPB3 in Bladder Cancer Prognosis and Progression
por: Gianniou, Despoina D., et al.
Publicado: (2023)

The Role of the Arginine in the Conserved N-Terminal Domain RLFDQxFG Motif of Human Small Heat Shock Proteins HspB1, HspB4, HspB5, HspB6, and HspB8
por: Shatov, Vladislav M., et al.
Publicado: (2018)

The small heat shock protein HSPB1 protects mice from sepsis
por: Breed, Elise R., et al.
Publicado: (2018)

The Role of the Heat Shock Protein B8 (HSPB8) in Motoneuron Diseases
por: Rusmini, Paola, et al.
Publicado: (2017)

The Small Heat Shock Protein, HSPB1, Interacts with and Modulates the Physical Structure of Membranes
por: Csoboz, Balint, et al.
Publicado: (2022)

Heat shock protein 27 phosphorylation state is associated with cancer progression
por: Katsogiannou, Maria, et al.
Publicado: (2014)

UVC irradiation suppresses platelet-derived growth factor-BB-induced migration in human pancreatic cancer cells
por: KAWAGUCHI, JUNJI, et al.
Publicado: (2011)

Heat shock proteins HSPB8 and DNAJC5B have HCV antiviral activity
por: Braga, Ana Claudia Silva, et al.
Publicado: (2017)

Small heat-shock protein HSPB3 promotes myogenesis by regulating the lamin B receptor
por: Tiago, Tatiana, et al.
Publicado: (2021)

The Tudor-domain protein TDRD7, mutated in congenital cataract, controls the heat shock protein HSPB1 (HSP27) and lens fiber cell morphology
por: Barnum, Carrie E, et al.
Publicado: (2020)

Cisplatin and ultra-violet-C synergistically down-regulate receptor tyrosine kinases in human colorectal cancer cells
por: Kawaguchi, Junji, et al.
Publicado: (2012)

The role of small heat-shock protein αB-crystalline (HspB5) in COPD pathogenesis
por: Cherneva, Radostina V, et al.
Publicado: (2012)

Dissecting the Functional Role of the N-Terminal Domain of the Human Small Heat Shock Protein HSPB6
por: Heirbaut, Michelle, et al.
Publicado: (2014)

Dioleoylphosphatidylglycerol Inhibits Heat Shock Protein B4 (HSPB4)-Induced Inflammatory Pathways In Vitro
por: Fowler, Teresa E., et al.
Publicado: (2023)

Heat shock protein B7 (HSPB7) inhibits lung adenocarcinoma progression by inhibiting glycolysis
por: Chen, Zhitao, et al.
Publicado: (2023)

The Small Heat Shock Protein HSP25/27 (HspB1) Is Abundant in Cultured Astrocytes and Associated with Astrocytic Pathology in Progressive Supranuclear Palsy and Corticobasal Degeneration
por: Schwarz, Lisa, et al.
Publicado: (2010)

Clinical, prognostic, and therapeutic significance of heat shock protein 27 in bladder cancer
por: Lee, Myung-Shin, et al.
Publicado: (2018)

The small heat shock protein B8 (HSPB8) modulates proliferation and migration of breast cancer cells
por: Piccolella, Margherita, et al.
Publicado: (2017)

Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells
por: Nakashima, Masanori, et al.
Publicado: (2011)

Alpha-glucosidase inhibitor use is associated with decreased colorectal neoplasia risk in patients with type 2 diabetes mellitus receiving colonoscopy: a retrospective study
por: Horibe, Yohei, et al.
Publicado: (2017)

Development of a Novel Scoring System for Predicting the Risk of Colorectal Neoplasia: A Retrospective Study
por: Ohno, Tomohiko, et al.
Publicado: (2016)

Heat Shock Protein 27 Phosphorylation Regulates Tumor Cell Migration under Shear Stress
por: Zhang, Baohong, et al.
Publicado: (2019)

Quaternary Structure and Hetero-Oligomerization of Recombinant Human Small Heat Shock Protein HspB7 (cvHsp)
por: Muranova, Lydia K., et al.
Publicado: (2021)

Heat Shock Proteins 27, 70, and 110: Expression and Prognostic Significance in Colorectal Cancer
por: Hrudka, Jan, et al.
Publicado: (2021)

Inhibition of heat shock protein 27 phosphorylation promotes sensitivity to 5-fluorouracil in colorectal cancer cells
por: MATSUNAGA, ATSUSHI, et al.
Publicado: (2014)

Phosphorylation of Heat Shock Protein 27 is Increased by Cast Immobilization and by Serum-free Starvation in Skeletal Muscles
por: Kim, Mee-Young, et al.
Publicado: (2014)

Heat shock protein 27 as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma
por: Schäfer, Claus, et al.
Publicado: (2012)

Localization of Heat Shock Protein 27 (Hsp27) in the Rat Gingiva and its Changes with Tooth Eruption
por: Sasaki, Au, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_bk4sddr5ngua5f68fobe1r2unr