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Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014
Childhood cancer remains the leading cause of disease-related death among children 0 to 14 years and incidence varies by race, ethnicity, sex, geographic locale, and age at onset. However, data are unavailable in some regions, indicative of a need for such information for cancer awareness, education...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730440/ https://www.ncbi.nlm.nih.gov/pubmed/26703649 http://dx.doi.org/10.3390/ijerph13010049 |
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author | Holmes, Laurens Vandenberg, Jonathan McClarin, Lavisha Dabney, Kirk |
author_facet | Holmes, Laurens Vandenberg, Jonathan McClarin, Lavisha Dabney, Kirk |
author_sort | Holmes, Laurens |
collection | PubMed |
description | Childhood cancer remains the leading cause of disease-related death among children 0 to 14 years and incidence varies by race, ethnicity, sex, geographic locale, and age at onset. However, data are unavailable in some regions, indicative of a need for such information for cancer awareness, education and prevention program. We utilized retrospective epidemiologic design to assess and characterize pediatric tumors in the Nemours Electronic Medical Records, between 2004 and 2014. Tumor frequency and children population size were used to determine the period prevalence as cumulative incidence (CI) proportion, as well as chi-square and Poisson Regression. The CI for overall childhood cancer in Delaware was 234 per 100,000 children, and varied by race, black (273 per 100,000), white (189 per 100,000). Similarly, sex variability was observed in CI, boys (237 per 100,000) and girls (230 per 100,000). The most commonly diagnosed malignancies were acute lymphoblastic leukemia (ALL), Central Nervous System (CNS)/brain and renal cancer. The geographic locales with relatively higher cancer CI in the state of DE were zip codes 19804 and 19960, but this does not imply cancer clustering. Differences in overall childhood cancer distribution occurred by race, sex, geography, and age. These findings are indicative of the need for cancer-specific health education, awareness and prevention programs in reducing the observed disparities in Delaware. |
format | Online Article Text |
id | pubmed-4730440 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-47304402016-02-11 Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 Holmes, Laurens Vandenberg, Jonathan McClarin, Lavisha Dabney, Kirk Int J Environ Res Public Health Article Childhood cancer remains the leading cause of disease-related death among children 0 to 14 years and incidence varies by race, ethnicity, sex, geographic locale, and age at onset. However, data are unavailable in some regions, indicative of a need for such information for cancer awareness, education and prevention program. We utilized retrospective epidemiologic design to assess and characterize pediatric tumors in the Nemours Electronic Medical Records, between 2004 and 2014. Tumor frequency and children population size were used to determine the period prevalence as cumulative incidence (CI) proportion, as well as chi-square and Poisson Regression. The CI for overall childhood cancer in Delaware was 234 per 100,000 children, and varied by race, black (273 per 100,000), white (189 per 100,000). Similarly, sex variability was observed in CI, boys (237 per 100,000) and girls (230 per 100,000). The most commonly diagnosed malignancies were acute lymphoblastic leukemia (ALL), Central Nervous System (CNS)/brain and renal cancer. The geographic locales with relatively higher cancer CI in the state of DE were zip codes 19804 and 19960, but this does not imply cancer clustering. Differences in overall childhood cancer distribution occurred by race, sex, geography, and age. These findings are indicative of the need for cancer-specific health education, awareness and prevention programs in reducing the observed disparities in Delaware. MDPI 2015-12-22 2016-01 /pmc/articles/PMC4730440/ /pubmed/26703649 http://dx.doi.org/10.3390/ijerph13010049 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Holmes, Laurens Vandenberg, Jonathan McClarin, Lavisha Dabney, Kirk Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title | Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title_full | Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title_fullStr | Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title_full_unstemmed | Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title_short | Epidemiologic, Racial and Healthographic Mapping of Delaware Pediatric Cancer: 2004–2014 |
title_sort | epidemiologic, racial and healthographic mapping of delaware pediatric cancer: 2004–2014 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4730440/ https://www.ncbi.nlm.nih.gov/pubmed/26703649 http://dx.doi.org/10.3390/ijerph13010049 |
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